The Boeing 737 had taken off from Moscow and was trying to land but
exploded on impact at about 19:20 local time (15:20 GMT), officials
said.
The Emergencies Ministry said there were 44 passengers and six crew members on the Tatarstan Airlines flight.
Investigators are now looking at whether a technical failure or crew error may have caused the crash.
Investigative committee official Vladimir Markin told Rossiya
24 TV that experts were checking whether poor quality fuel and weather
conditions could have been contributing factors.
It was raining in Kazan when the aircraft crashed.
Among the dead was Irek Minnikhanov, a son of the president
of the Russian Republic of Tatarstan, according to the official
passenger list.
Aleksander Antonov, who headed Tatarstan's branch of the Federal Security Service, was also among the passengers.
The UK Foreign Office confirmed that a British national died in the crash.
"We are in touch with local authorities and providing consular assistance to those affected," it said in a statement.
The victims also included two children.
Russian President Vladimir Putin "expressed his condolences
to the relatives of the victims in this horrible disaster", his
spokesman Dmitry Peskov was quoted by the news agency Interfax as
saying.